MiSeq Sequencer : Empowering Genomic Exploration with Simplicity and Affordability 

The MiSeq Sequencer is a user-friendly and cost-effective benchtop solution, making it an ideal choice for laboratories entering the realm of Next-Generation Sequencing (NGS) or operating under budget constraints. Offering seamless operation, it has the capacity to generate up to 15 million reads per run, boasting read lengths of up to 300 base pairs

The MiSeq Sequencer serves as a reliable tool for laboratories looking to embrace NGS technology without compromising on quality or budget. Its seamless operation and substantial read capacity make it an asset for a variety of genomic research applications.

Whether you are venturing into NGS for the first time or managing limited financial resources, the MiSeq Sequencer stands as a valuable solution, empowering your laboratory to unlock the potential of genomics with efficiency and affordability.

User-Friendly Design:

Benchtop Sequencer: Tailored for ease of use, the MiSeq Sequencer ensures a straightforward and efficient sequencing experience.


Budget-Friendly Solution: Suited for laboratories with limited financial resources, the MiSeq provides a cost-effective entry into the world of NGS.

Performance Capacity:

Read Output: Capable of producing up to 15 million reads per run, facilitating high-throughput sequencing projects.

Read Lengths:

Versatile Read Lengths: With read lengths extending up to 300 base pairs, the MiSeq accommodates diverse genomic exploration needs.

  • Wavelengths: 532 nm, 457 nm, 655 nm
  • W × D × H: 86.4 cm (34 in) × 93.3 cm (36.7 in) × 158.8 cm (62.5 in) with monitor
  • Dry weight of instrument (not including UPS; no core consumables): 1171 lb
  • Dry weight of instrument (including UPS; no core consumables): 1253 lb
  • Wet weight of instrument (not including UPS; loaded with core consumables): 1296 lb
  • Crated weight of instrument: 1591 lb (722 kg)
  • Accessories pallet weight: 525 lb (238 kg)

View In-Depth Spec Sheet (PDF)

MiSeq Revolutionizes Research with Automated End-to-End Sequencing Workflow


Automated, on-instrument data analysis workflows help researchers to take their research further. MiSeq is the only personal sequencer capable of producing paired-end reads, and it puts the largest portfolio of sequencing applications on the benchtop. Optimized sample preparation kits, push-button sequencing, and automated data analysis create the first truly end-to-end sequencing workflow.

Breakthrough technology innovations delivering a leap forward in sequencing

Broad Applications Base

The MiSeq System facilitates your research with a wide range of sequencing applications. It is capable of automated paired-end reads and up to 15 Gb per run, delivering over 600 bases of sequence data per read. The library prep kits that it uses are optimized for a variety of applications, including targeted gene, small genome, and amplicon sequencing, 16S metagenomics, and more.

Integrated, Optimized Library Prep

Library prep kits prepare input RNA or DNA for a diverse range of applications such as whole-genome and targeted region resequencing, transcriptome analysis, and expression profiling. Each library prep method is optimized to fit each unique application, and most are available in a variety of throughput and multiplexing configurations.

Simple NGS Workflow

The MiSeq System can go from DNA to data in just over 8 hours. A compact, all-in-one platform incorporates cluster generation, paired-end fluidics, sequencing by synthesis chemistry, and data analysis. An intuitive touch screen and plug-and-play reagents with RFID tracking add convenience. The MiSeq System eliminates the need for auxiliary hardware and computing resources, saving valuable lab bench space. Seamless data upload to BaseSpace Sequence Hub enables analysis, collaboration, and security.

User-Friendly, Intuitive Software

System software guides you through sample sheet creation and setup prior to a run, then walks you through flow cell and reagent loading steps. Control software overviews quality statistics you can monitor as the run progresses. Once primary analysis completes, reporting software launches and automatically analyzes the data quality and coverage information of each sample.