Clean-up and Size Selection

All clean-up and size selection products below from Beckman Coulter Life Sciences use Solid Phase Reversible Immobilization (SPRI) paramagnetic bead-based chemistry

AMPure XP

  • Remove contaminants (dNTPs, salts, primers, primer dimers) throughout any NGS workflows.
  • Manual and automated
  • High recovery of amplicons > 100 bp
  • Predictable and consistent size selection

RNAClean XP

  • Purify RNA and cDNA from common enzymatic reactions
  • Manual and automated
  • Complete removal of salts, unincorporated primers and dNTPs
  • Used in RNA-Seq library preparations
  • Certified RNAse-free

CleanSEQ

  • A rapid, high-performance dye-terminator removal process
  • Requires no centrifugation or filtration
  • Performed manually or fully automated for high-throughput
  • Produces sequences with longer Phred 20 read lengths and higher signal intensities

SPRIselect

  • Purify DNA fragments of the desired size for library preparation
  • Tunable fragment size selection to suit specific applications
  • Predictable, consistent size selection between runs and reagent lots
  • Compatibility with manual and automated processing